Review Article: Comparison of Antioxidant Activity Using the DPPH Method in Ten Liquid Soap Formulations of Medicinal Plant Extracts
DOI:
https://doi.org/10.37277/sfj.v19i2.2656Keywords:
antioxidant, DPPH, medicinal plant extract, liquid soapAbstract
Antioxidants play a crucial role in inhibiting the activity of free radicals, one of which is through the use of medicinal plant extracts as ingredients in the production of liquid soap, a skin care product with additional benefits. This study aims to compare the antioxidant capacity of ten liquid soap products containing medicinal plant extracts using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. The method used was a literature review involving an analysis of ten scientific articles obtained from the Google Scholar database using the keywords “liquid soap”, “plant extracts” and “antioxidants.” between 2017 and 2025. The results of the study showed that all plant extracts analyzed exhibited antioxidant activity with varying IC₅₀ values. Guava leaf extract (Psidium guajava L.) demonstrated the highest antioxidant activity, falling into the “very strong” category with an IC₅₀ value of 1.17 µg/mL. This was followed by beet root extract with an IC₅₀ of 88.13 ppm, watermelon extract with an IC₅₀ of 91.92 ppm, cassava peel with an IC₅₀ of 96.42 ppm, and green tea leaves at a concentration of 6%, which Followed by beet root extract with an IC₅₀ of 88.13 ppm, watermelon extract with an IC₅₀ of 91.92 ppm, cassava peel with an IC₅₀ of 96.42 ppm, and green tea leaves at a 6% concentration with an IC₅₀ of 98.61 ppm, all of which fall into the “strong” category. Papaya leaf extract had an IC₅₀ value of 103.89 ppm, placing it in the moderate category. Meanwhile, Robusta coffee beans with an IC₅₀ of 238.15 ppm, African leaves with an IC₅₀ of 261.31 ppm, and tomatoes with an IC₅₀ of 425.67 ppm fell into the weak to inactive category. These differences in antioxidant activity are influenced by the type of extract used, the concentration applied, and the formulation process. It can be concluded that liquid soap containing medicinal plant extracts has potential as a skin care product with antioxidant activity; however, further optimization of the formulation is still needed to improve its stability and effectiveness.
References
Agustina, L., Yulianti, M., Shoviantari, F., & Sabban, I. F. (2017). Formulasi dan Evaluasi Sabun Mandi Cair dengan Ekstrak Tomat (Solanum lycopersicum L.) sebagai Antioksidan Formulation and Evaluation of Herbal Liquid Soap Containing Tomatoes ( Solanum lycopersicum L.) as Antioxidants. 104–110.
Astira, N. P. Y., & Putri, E. (2021). Uji Kualitas Red Velvet Cake Dengan Menggunakan Ekstrak Umbi Bit (Beta Vulgaris) Sebagai Bahan Pewarna. 1(1), 1–14. https://doi.org/10.23887/jk.v1i1.32811
Ayu, D. F., Johan, V. S., & Wardana, N. (2025). Penambahan ekstrak umbi bit (Beta vulgaris L.) sebagai antioksidan dalam sabun mandi cair. 19(3), 616–624. https://doi.org/10.21107/agrointek.v19i3.17142
Berawi, K. N. & Marini, D.(2018). Efektivitas Kulit Batang Bakau Minyak ( Rhizopora apiculata ) sebagai Antioksidan The Effectiveness Rhizopora apiculata Bark as an Antioxidant. 5, 412–417.
Ciputra, A. (2018). Klasifikasi Tingkat Kematangan Buah Apel Manalagi dengan Algoritma Naive Bayes dan Ekstraksi Fitur Citra DIigital. 9(1), 465–472.
Ii, B.A.B. (1999). Vernonia. : Vernonia amygdalina.
Ikhsanudin, M. A., Setyati, E., & Junaedi, H. (2023). Deteksi tingkat kemanisan buah semangka ( citrullus lanatus ) berdasarkan ciri kulit buah dengan menggunakan metode cnn (convolutional neural network). 8(4), 1501–1513.
Kang Sing Lung, J., & Pramita Destiani, D. (2017). Review Article Uji Aktivitas Antioksidan Vitamin A, C, E dengan metode DPPH. Jurnal Farmaka, 15(1), 53–62. https://jurnal.unpad.ac.id/farmaka/article/view/12805/pdf
Kesuma Sayuti, R. Y. (2015). Antioksidan Alami dan Sintetik. Andalas University Press.
Maera Zasari, Kartika Kartika, D. A. (2023). Eksplorasi-Karakterisasi Morfologi Kopi Robusta Lokal di Pulau Bangka. 34(2), 200–209.
Maulana, A. (2021). Identifikasi Senyawa Pektin Dari Ekstrak Kulit Singkong ( Manihot esculenta ).
Meilina, R., & Japnur, I. S. (2020). Aktivitas Antioksidan Formulasi Sediaan Sabun Cair Dari Buah Apel ( Malus Domesticus ) Antioxidant Activities For Liquid Soap Formulation From Apple Fruit (Malus Domesticus). 6(1), 404–410.
Mu’Nisa. (2023). Antioksidan pada Tanaman dan Perananya Terhadap Penyakit Degeneratif. Brilian Internasional Surabaya.
Munawara, M. (2021). Efek Penambahan Asam Askorbat Terhadap Karakteristik Fisik Dan Aktivitas Antibakteri Hand Sanitizer Ekstrak Cair Etanol Teh Hijau (Camellia sinensis L.).
Novita, R. R., Daskar, A., Suswidiantoro, V., & Rosanti, A. S. (2025). Formulasi Dan Uji Aktivitas Antioksidan Sediaan Sabun Cair Ekstrak Daun Pepaya (Carica papaya L.) Menggunakan Metode. 5(3), 24613–24627.
Oil, C., Variasi, D., Infused, K., & Teh, O.I L. (2021). Liquid Soap Making From Castor Oil With Various Infused Oil. Jtip Indonesia, 11(01), 11–18.
Puji, T., Sudarwati, L., Kusumo, G. G., Fernanda, M. A. H. F., Soedarti, T., & Soegianto, A. (2021). Bioautography of Ethanol extract from Carica papaya leaves for antimicrobial activity against Staphylococcus aureus , E . coli and Bacillus subtillis. 27(2).
Ramadian, D., Dewi, H., Zulhamidi, Z., Rizki, A., & Amris, A. (2019). Pelatihan Pembuatan Sabun Cair dan Sabun Transparan di Kenagarian Pasie Laweh. 2(2), 2–5.
Saehu, A., Suryani, N., & Noviyanto, F. (2022). Biogenerasi. 7(2), 124–135.
Sari, F., Kurniaty, I., & Susanty, S. (2021). Aktivitas Antioksidan Ekstrak Daun Jambu Biji (Psidium Guajava L) sebagai Zat Tambahan Pembuat Sabun Cair. 10(01).
Sasmita, A. N., Turahman, T., & Harmastuti, N. (2023). Formulasi dan uji aktivitas antioksidan sabun cair badan ekstrak etanol daun teh hijau (Camellia sinensis L.) dengan metode DPPH Formulation and antioxidant activity of soap liquid body from ethanol extracts of green bermanafaat sebagai antioksidan dik. 7(1), 1–13.
Snyder, H. (2019). Literature review as a research methodology : An overview and guidelines. Journal of Business Research, 104(July), 333–339. https://doi.org/10.1016/j.jbusres.2019.07.039
Srianti, S., Putri, R. A., & Annisa, A. (2024). Klasifikasi Jenis Daun Jambu Biji Menggunakan Metode Conten Based Image Retrifial (CBIR) dan Support Vector Machine ( SVM ). 4307(May), 806–811.
Sukamwati, S., Subagja, I. I., & Tantri, E. (2025). Jurnal Medika Farmaka. 3(24), 318–325. https://doi.org/10.33482/jmedfarm.v3i2.66
Triyanti, S. B., Lestari, F. P., Anisa, P., Fitriana, N., & Rostiana, H. R. (2025). Pengaruh Metode Ekstraksi Maserasi , Sonikasi , dan Sokletasi Terhadap Nilai Rendemen Sampel Kulit Buah Naga (Hylocereus polyrhizus). 8(1), 71–78.
Wardani, H. A., & Handoko, W. T. (2017). Efektivitas Ekstrak Daun Afrika (Vernonia amygdalina Del) sebagai Analgesik pada Jantan dengan Metode Geliat. 47–53.
Wardani, R. I., Wardani, T. S., & Fitriawati, A. (2024). Formulasi Dan Evaluasi Sabun Mandi Cair Dengan Penambahan Filtrat Semangka (Citrullus Lanatus ( Thunb.) Matsum & Nakai ) sebagai Antioksidan Dengan Metode DPPH. 4(1), 145–157. https://doi.org/10.37311/ijpe.v4i1.24749
Wulandari, T. (2025). Karakter Morfologi dan Sitologi Tanaman Tomat (Solanum lycopersicum L.) Hasil Induksi Ekstrak Tanaman Tapak Dara (Catharantus roseues (L.) G.Don).
